This class will explore the use of psilocybin (commonly termed "magic mushrooms) in current clinical trials for relief from drug-resistant depression, PTSD, alcohol and nicotine addiction, and more. The history of its use in spiritual practices, as a recreational drug, and as a clinical therapeutic will be reviewed. Legalization of this substance raises both medical and societal challenges. This class will arm the listeners with facts with which to make their own decisions.